Salinomycin är en fodertillsats av gruppen koccidiostatika som ämnen avsedda att döda eller hindra tillväxten av parasitiska protozoer (encelliga organismer). Salinomycin in är endast tillåtet i vissa fjäderfäfoder och kan vara skadligt för andra djurslag.

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Salinomycin sodium, Sodium salinomycin: SMILES: CCC(C1CCC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C(=O)O.[Na+] Storage: Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of

Salinomycin (Procoxacin) shows selective activity against human cancer stem cells. - Mechanism of Action & Protocol. Salinomycin Na+ ionophores are metabolized in the liver by cytochrome P450 enzymes, and are excreted mostly into bile and feces as parent compound and metabolites in poultry. Following oral administration, residues are present only at very low concentrations in liver and muscle that fall below the limit of decision of the assay within 2 days in poultry.

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action of salinomycin. Salinomycin shows cyto- toxic effect by disrupting the balance of sodium and potas- sium ions across the cell membrane and the  Visit ChemicalBook To find more Salinomycin(53003-10-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula  “To investigate its action, we developed a surrogate salinomycin drug, ironomycin, that was at least 10-fold more potent than salinomycin against CSCs in vitro and  Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. Salinomycin (Procoxacin),一种钾离子载体抗生素,选择性抑制革兰氏阳性菌的 生长(gram-positive bacteria)。Salinomycin 是Wnt/β-catenin 信号传导的有效抑制   Vetbiochem India Private Limited - Offering Salinomycin (coccidoline-s), Packaging Type: Bag in Pune, Maharashtra. Get best price and read about company. Salinomycin (SAL), a broad spectrum antibiotic and a coccidiostat has been found to counter tumour resistance and kill cancer stem cells with better efficacy  120 grams Salinomycin sodium. Mechanism of Action: Salinocox® is an Ionophore coccidiostat that forms fat soluble complexes with Sodium and Potassium ions  21 Mar 2018 Sacox® microGranulates, containing salinomycin sodium (SAL-Na), for chickens for fattening and chickens reared for laying have been  Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug.

Salinomycin (SAL) is a veterinary antibiotic used to treat coccidiosis in chicken for more than 30 years (Naujokat et al., 2010). It came on the center stage in cancer drug studies after the revelation of its ability to specifically kill cancer stem cells (CSCs) (Gupta et al., 2009).

In solution, store at -20ºC and use within 3 months to prevent loss of Översättnings-API; Om MyMemory; Logga in Salinomycin analogs: Mechanistic probes and structure–activity relationships against cancer stem cells. Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning) 2019-11-25 · Salinomycin is administered to cancer patients via intravenous injection.

SALINOMYCIN SODIUM. Salinomycin sodium salt. Salinomycin (sodium salt) UNII-92UOD3BMEK. 55721-31-8

Salinomycin (Procoxacin) shows selective activity against human cancer stem cells. - Mechanism of Action & Protocol. Salinomycin Na+ ionophores are metabolized in the liver by cytochrome P450 enzymes, and are excreted mostly into bile and feces as parent compound and metabolites in poultry. Following oral administration, residues are present only at very low concentrations in liver and muscle that fall below the limit of decision of the assay within 2 days in poultry. Salinomycin (Procoxacin) is an antibacterial and coccidiostat ionophore therapeutic agent. Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling.

Salinomycin

— ≤ 10 g 18,19- dihydrosalinomycin/kg salinomycin sodium. — ≤ 10 g methylated salinomycin/kg salinomycin sodium. Analytical method (1) For the quantification of salinomycin in … Salinomycin reduces the proportion of cancer stem cells(CSC) by >100-fold relative to paclitaxel, a commonly used breast cancer chemotherapeutic drug. Millipore Salinomycin S4526-5MG | Sigma-Aldrich.
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Salinomycin

Genom att använda salinomycin mot cancerceller som odlas i hypoxi hoppas jag se en större effekt på cancerstamceller eftersom hypoxi leder till fler stamcellsliknande egenskaper. Salinomycin och hypoxi Salinomycin induces apoptosis of human colorectal cancer cells, accompanied by accumulation of dysfunctional mitochondria and reactive oxygen species.

69 p. Salinomycin is a polyether ionophore with broad spectrum Gram positive and anti-coccidial activity.
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Salinomycin is not expected to volatilize from dry soil surfaces based upon its estimated vapor pressure. Salinomycin was degraded 50-70% in soil in 7 day aerobic studies, 20-25% was attributed to abiotic reactions and the remaining portion was considered biodegradation.

Salinomycin Na+ ionophores are metabolized in the liver by cytochrome P450 enzymes, and are excreted mostly into bile and feces as parent compound and metabolites in poultry. Following oral administration, residues are present only at very low concentrations in liver and muscle that fall below the limit of decision of the assay within 2 days in poultry.